This article explores the rise of Runes in the Bitcoin ecosystem and its market performance, and analyzes its potential in the fields of cross-chain transactions, decentralized finance (DeFi) and NFT. As the Bitcoin market picks up, the transaction volume and market value of Rune Protocol have increased significantly, becoming an important force in the Bitcoin ecosystem. At the same time, the current challenges faced, such as technical bottlenecks and market confidence fluctuations, and how Rune Protocol can achieve innovation through innovation are discussed. Mechanism improves user experience and liquidity.